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The safety data available derive from Phase 2 clinical trials (Jastreboff et al., NEJM, 2023), which, whilst informative, represent a relatively limited population and duration of follow-up compared to post-marketing surveillance
DSIP was originally identified as a naturally occurring peptide associated with sleep physiology, although commercially available DSIP products are manufactured synthetically
Its triple-hormone approach could offer hope for people who haven't achieved their goals with current medications
This peptide was also associated with a reduction in coarse wrinkles and mottled pigmentation
Understanding metabolic adaptation during weight loss explains why this matters
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