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Critically, GHK-Cu delivers copper as cofactor for lysyl oxidase and lysyl hydroxylase, copper-dependent enzymes essential for collagen cross-linking and stability

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some protocols include 3-month-on / 6-week-off cycling

Blots were imaged with a ChemiDoc MP Imaging system (Bio-Rad)

While familial ALS is typically caused by hereditary genetic mutations, the cause of sporadic ALS (comprising 90% of all cases) is not completely understood