Long-term mildronate treatment increased Proteobacteria level in gut microbiome, and caused behavioral deviations and transcriptome change in liver, heart and brain of healthy mice
doi:10.1056/NEJMoa2502082
orders over $50, which covers any NAD+ Support purchase, but the company only ships within the U.S., U.K., Ireland, Australia, New Zealand, and Canada at this time
However, unlike branded medicines, these compounds are not FDA-approved because no clinical trials have tested their safety and effectiveness
Retinal microcirculation: a window into systemic circulation and metabolic disease
[PMID: 22561244] PubMed record related to this compound for laboratory literature review