[4] [7] Major adverse cardiovascular events (MACE)comprising cardiovascular death, non-fatal myocardial infarction, and non-fatal strokeoccurred at rates comparable to or lower than comparator treatments
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This is not an exhaustive list and your healthcare provider should take a detailed history
Conclusion This comprehensive review highlights the therapeutic potential of GLP-1 and its analogs in the management of metabolic disorders, particularly T2DM
Managing Reactions If injection site reactions occur: Ice the area for 10 minutes before injection to numb it Take an antihistamine (diphenhydramine 25mg) 30 minutes beforehand Apply hydrocortisone cream after injection to reduce itching Switch to a different injection site area Long-Term Safety Considerations Because Retatrutide is still in Phase 3 clinical trials, our longest safety data comes from the 48-week Phase 2 study
Update: This kept getting worse and using a smaller needle didn't help, so I'm going to switch to once-weekly injections and also dilute the drug with significantly less reconstitution solution (20 mg / mL)