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The positive recommendation in based on condition of submitting the complete Clinical Study Report (CSR) of the 240-week long ESSENCE trial and confirmation of safety and clinical benefit of semaglutide 2.4 mg injection based on the trial final results
food and drug administration
Ces peptides ont t conus pour mimer laction de ces hormones (ce quon appelle en pharmacologie un effet agoniste) sur le contrle de la glycmie : suite labsorption de sucre, le GLP-1 et le GIP scrts par les cellules de lintestin permettent en effet daugmenter de faon trs importante la production dinsuline par le pancras, des taux trs suprieurs ceux qui sont produits simplement en rponse la prsence de sucre dans le sang (Figure 1)
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Oral contraceptives, antibiotics and narrow therapeutic index drugs may show altered absorption kinetics
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