Essentially, after the medication was approved for obesity, GLP-1RA use took off so quickly that we lost control and vision of how fast people were picking up these medications, and the trends of use are uncertain, said Ali Rezaie MD, MSc, FRCPC, medical director of the Cedars-Sinai GI Motility Program and director of bioinformatics at the Medically Associated Science and Technology program at Cedars-Sinai
This is primarily seen in research settings and may produce faster or greater weight loss, but the safety profile of the combination is not yet fully established
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Research is already underway on GLP-1 and overeating, nicotine use and other forms of addictive behavior