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Supported in part by Award Number P30 CA006927 from the National Cancer Institute of the National Institutes of Health
Finally, knockdown of ACLY or TMLHE alone increased sensitivity to DNA-damaging agents, and this effect was additive on double knockdown (Fig
Gut Pathogens, 10
For example, doxorubicin (DOX) has cardiac side effects that lead to irreversible dilated cardiomyopathy and congestive heart failure, and acetylcarnitine has been shown to prevent cardiac functional and structural damage caused by DOX-induced oxidative stress [289]
Nevertheless, lactate simultaneously exerts immunomodulatory effects in sepsis
Long-term treatment with these antibiotics increases the excretion of pivaloyl-carnitine, which can lead to a lack of carnitine
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