POPs are mainly excreted through conjugation with GSH and this mechanism is extremely important for the health status, since exposure to POPs has been associated to diabetes, cardiovascular diseases and many other chronic diseases (1, 13)
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therefore, it is advised that patients older than 50 years and vegans or strict vegetarians should consume foods fortified with vitamin B12 or take vitamin B12 supplements to avoid vitamin B12 deficiency
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Dose: Most vitamin B12 supplements contain rather high doses
Users who run continuous high-dose protocols often report diminishing returns, while those who cycle seem to maintain consistent responses over months and years of use