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13 Less common but important side effects include: Gallstones (rare) Kidney problems, especially in older adults who already have kidney disease Significant weight loss, which could be concerning for frail elderly people Special considerations for older adults: Stomach problems can lead to dehydration, which can be more serious in older adults

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Good sources that do not exacerbate bloating include cooked vegetables (broccoli, carrots, green beans), berries, oatmeal, lentils, and chia seeds

In an analysis of similar patients, the risk of heart attack was reduced by 28%

The proposed modulation of the PB, via indirect inhibition of AgRP by GLP-1, could also aid in the modulation of the BST by removing AgRP-mediated inhibition of this nucleus, thereby enabling and potentially enhancing the appetite-reducing PB-to-BST pathway