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Kidney function: In some cases, tirzepatide may affect kidney function
As with all GLP-1based therapies, individual outcomes vary depending on adherence, baseline metabolic health, dose optimisation, and lifestyle support
This often causes significant alarm for patients
| Co-prescribed Drug | Interaction Pathway | Effect on Co-Drug | Severity | Clinical Action | |---|---|---|---|---| | Warfarin | Hepatic CYP2C9 induction (GCGR) | Reduced anticoagulant effect
Davidson JA, Brett J, Falahati A, Scott D
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