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"SURMOUNT-1: Tirzepatide Once Weekly for the Treatment of Obesity." ACC.org Wilding JPH, et al
This effect often results from the potent antioxidant activity clearing oxidative stress
Vetter ML, Wadden TA, Teff KL, Khan ZF, Carvajal R, Ritter S, et al
In short, GLP-1 does everything a diabetes drug should do
The review revisited SUSTAIN-6, where semaglutide-treated patients showed a hazard ratio of 1.76 for retinopathy complications compared with placebo. The discussion has since shifted toward whether rapid metabolic changerather than direct retinal toxicitymay explain the signal