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doi: 10.1007/s11033-025-10632-x

Reference: Association between GLP-1 receptor agonist use and worsening mental illness in people with depression and anxiety in Sweden: a national cohort study by Heidi Taipale, Mark Taylor, Markku Lhteenvuo, Ellenor Mittendorfer-Rutz, Antti Tanskanen and Jari Tiihonen, April 2026, The Lancet Psychiatry

Potential drug interactions Sermorelin Nasal Spray has no known major drug interactions, but may have the following interactions with certain drugs: Glucocorticoids (prednisone) May blunt growth hormone (GH) release Oral estrogens May increase IGF-1 resistance Insulin or sulfonylureas May alter glycemic control Somatostatin analogs May antagonize Sermorelins effects Dopamine antagonists May disrupt human growth hormone (HGH) regulation GABAergic meds May reduce pulsatility of HGH release Beta blockers (Metoprolol or Propranolol) Other secretagogues/peptides May result in unsafe levels of HGH Other important safety information Sermorelin Nasal Spray is only for patients who are at least 30 years old

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