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Most research is on rats and mice
Zhang C, Liu Z, Wang F, Zhang B, Zhang X, Guo P, et al
Trabecular (spongy) bone in vertebrae and long bone ends differs from cortical (dense) bone in shafts, affecting healing characteristics
The recognised reasons above, particularly the shift in potassium and the body adjusting to corrected levels, explain the symptoms without needing a detox theory
In a randomized, double-blind, placebo-controlled trial in 2,919 participants (65 years) with elevated blood concentrations of homocysteine, supplementation with vitamin B 12 (500 g/day) and folic acid (400 g/day) for two years did not decrease the risk of osteoporotic fracture despite reductions in homocysteine (120, 121)
BPC-157 physician prescribing carries the most consumer awareness and arguably the most scrutiny, given how openly it circulates on Reddit and X
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