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IGF-1 LR3 is more potent than regular IGF-1 because of the decreased binding of Long R3 IGF-1 to IGF binding proteins, allowing it to remain active up to 120 times longer compared to native IGF-1

Baserga et al, 1997)

Regarding weight loss, the SURMOUNT-1 trial revealed meaningful results, with participants achieving body weight reductions of up to 20.9% when treated with 15 mg doses over 72 weeks [46]

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However, we feel that our robust study design achieved our study goals in a challenging, well-defined population of preschool children