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Native GLP-1 and AMG 133 both induce complete agonism of human GLP-1R, with respective EC 50 values of 4.1 and 24.4 pM (Extended Data Fig
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The body requires approximately 15 mg of carnitine per day, which is produced both internally and through nutrition
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Signals near GLP1R tracked with those stomach side effects, which fits the idea that stronger receptor activity can cut both ways
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