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Motility issues can happen anywhere from the esophagus, the stomach, small intestine or large intestine

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10.1016/j.medj.2021.10.004 17 CorrealeM.LamacchiaO.CiccarelliM.DattiloG.TricaricoL.BrunettiN

But if you have variations in both MTHFR-related genes, folate processing slows down noticeably and thats when more persistent symptoms can appear