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[5] Beyond injection site effects, some trial participants have reported more generalised skin symptoms, including diffuse pruritus and, in isolated cases, rash

These medications reduce hunger, cravings and the reward response to high-fat, high-sugar foods, helping people feel full with less food. For many patients, that shift shows up as quiet

Lincoff adds that it was known that semaglutide could help reduce the risk of cardiovascular events in those with diabetes, but it was unclear if that would also be the case in those without diabetes

Still, insurers and many patients remain eager to define an end point for the treatment