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Seifbarghi et al., 2017)

Unlike medication effects, which are usually aimed at altering action of one receptor or enzyme to ameliorate psychiatric symptoms [e.g., serotonergic pathway, glutamatergic pathway (57, 108)], the low glutamate diet aims to reduce glutamatergic excitotoxicity while concurrently increasing consumption of nutrients known to be protective against excitotoxicity, with the aim of improving neurotransmission (69, 109)

Nat Chem Biol

Metabolic changes typically emerge within twenty-five to thirty-two days as therapeutic bacterial strains establish populations and influence hormone secretion

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