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K-means clustering of amplicon sequence variant data confirmed that 5-Amino-1MQ treatment generated a distinct cecal microbiome profile from all other treatment groups including diet-switched vehicle controls indicating that NNMT inhibition produces microbiome changes that are separable from those produced by dietary composition alone

It is required for neurological function, DNA creation, red blood cell formation, homocysteine regulation (an amino acid recognized as being a marker for a number of diseases), and acts as a cofactor for a number of processes and reactions in the body

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