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Standard Clinical Trial Protocol The standard Retatrutide escalation schedule from Phase 2 trials follows a conservative 12-week path to maximum dose: This conservative approach minimizes gastrointestinal side effects by allowing your body time to adapt at each dose level

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The unknown rate constants for R 1 , R 2 , R 3 , R 4 and R 5 for the respective models were fitted using the LSQNONLIN function in MATLAB, a non-linear least squares solver

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