While more research is needed to understand the relationship between berberine and heart health, some initial research shows that the supplement may help increase your good (HDL) cholesterol while reducing your total cholesterol, bad (LDL) cholesterol and blood triglycerides
Convento, M., Pessoa, E., Arago, A., Schor, N
Owens OM et al
It is also not recommended for use in people with type 1 diabetes or diabetic ketoacidosis
If that describes you, understanding the interaction landscape is important
While that study used the 1.0 mg dose at steady state, the directional effects begin during the early weeks