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Telehealth businesses and med spas sometimes feature pictures of lean adults in their promotional materials, for example, but researchers dont yet know about the benefits and risks of GLP-1 drugs to people who are not overweight
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The use of GLP-1R agonists was associated with fewer intra-articular injections of steroids and a lower cartilage loss velocity from the medial femoral joint, but the direct effects of GLP-1R agonist, apart from the weight loss-mediated pathway, did not reach statistical significance
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More than 80 molecules are currently in development for obesity, with over 25 companies testing GLP-1s either as monotherapies or in combination with other agents
Animal studies have provided some mechanistic insights
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