A 2022 study involving people with Irritable Bowel Syndrome (IBS) found that ROSE 010, a GLP-1 receptor agonist, reduced IBS pain during flare-ups, primarily in female participants
So, the studys average13.7%weight loss likely brings considerable relief to the joints just from reducing that mechanical load. However, according to Singh, there may be more at play
Gastrointestinal Symptoms Nausea, bloating, and gastrointestinal discomfort are common side effects of GLP-1 medications, particularly early in treatment or after dose increases
Reduced food intake means less dietary iron
Vitamin B12 (cobalamin) deficiency in elderly patients
NTCP inhibitors may result in a significant increase in systemic exposure of zavegepant (a NTCP substrate)