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Tirzepatide further attenuates lipopolysaccharide (LPS)-induced left ventricular remodeling and dysfunction by inhibiting the TLR4/NF-B/NLRP3 inflammatory pathway (89)

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IGF-1 LR3 is a recombinant analog of human IGF-1 comprised of the complete IGF-1 sequence, with an Arginine substitution for the third position Glutamic acid, and a 13 amino acid length N terminus peptide extension

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It may cause dehydration, nutrient loss, and fatigue, especially if it continues over time