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Since mouse microbiome profiles often highly correlate with body weight and fat composition, this study was designed to test whether the cecal microbiomes of DIO mice treated with NNMTi and LD were comparable to the microbiomes of age-matched lean counterparts and distinct from microbiomes of DIO mice maintained on a high-fat Western diet (WD) or subjected to LD switch alone

JCI Insight 5 , e140532 (2020)

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However, high dose oral vitamin B12 therapy can also be effective, provided that the dose is sufficient, medication adherence is good, and a response is documented

Angiogenic mechanisms: Improved retinal blood flow on OCT angiography or fluorescein angiography

Oncolytic herpes virus rRp450 shows efficacy in orthotopic xenograft group 3/4 medulloblastomas and atypical teratoid/rhabdoid tumors