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The combined evidence from various trials also demonstrated a consistent benefit across trial designs, drug formulations, and patient populations, supporting the conclusion that the cardiovascular benefit is likely a class effect rather than an isolated finding

The effect is more weight loss than you get with drugs that hit only one receptor

The FDA has warned that some pharmacies may be improperly compounding semaglutide

In a SAXENDA clinical trial in adult patients with overweight (excess weight) or obesity with type 2 diabetes mellitus treated with basal insulin and SAXENDA in combination with a reduced-calorie diet and increased physical activity and up to 2 oral anti-diabetes medications, severe hypoglycemia was reported by 3 (1.5%) of 195 SAXENDA-treated patients and 2 (1%) of 197 placebo-treated patients

Not intended for diagnostic or therapeutic use

95% confidence interval [CI], -1.04 to -0.15