In research contexts, the complex has been explored for its potential to support extracellular matrix maintenance, barrier quality, and tissue remodeling signals, particularly when formulated for topical presentation
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SIRT1 is a histone deacetylase, which may regulate the transcriptional activity of BMAL1/CLOCK, forming a metabolic feedback loop again between the circadian clock system and metabolism (Nakahata et al., 2009
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This neuroprotective effect is particularly important for individuals who have suffered from traumatic brain injuries or those at risk of neurodegenerative conditions such as Alzheimers disease (Bataille & Letenneur, 2020)
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