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Besides glyoxalase 1, among numerous targets of the Nrf2 transcription factor are both antioxidant and antiglycation enzymes: superoxide dismutase, catalase, glutathione peroxidase, peroxiredoxin, thioredoxin reductase, -glutamylcysteine synthase, glutathione reductase, thioredoxine reductase, glutathione S-transferases, glutathione reductase (2, 8)

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Vegetarians or Vegans : Since B12 is primarily found in animal products, vegetarians or vegans may benefit from supplementation

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Maintenance Dose: Once B12 levels are normalized, a maintenance dose of 1,000 mcg monthly or every few months may be recommended

The first is by stimulating fibroblasts and promoting the formation of new blood vessels to help hair follicles receive the necessary nutrients for growth