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Cancer 71 , 39813987 (1993)

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40 In a mouse model, IL-12 was shown to be protective against thicker plaques, therefore inhibition may be counterproductive

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Patients in the trial receiving weekly retatrutide injections for 40 weeks lost more than four times as much weight as those on placebo, while the average drop in long-term blood sugar (HbA1c) was more than twice that of the placebo

The December 2025 phase 3 results confirmed retatrutides position