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In research contexts, the complex has been explored for its potential to support extracellular matrix maintenance, barrier quality, and tissue remodeling signals, particularly when formulated for topical presentation

Bear MF, Cooper LN, Ebner FF (1987)

Nevertheless, both dietary intakes of vitamin B12 and serum concentrations of vitamin B12 were unable to observe significant associations between NAFLD patients and controls in 317 Iranians (44) and 54 participants in Greece (15), respectively

The improvements could be due to placebo effect or the invasive procedure itself (cystoscopy), and subtle side effects might have gone unnoticed in such a small sample

Its results are cumulative

DSIP appears to help break this cycle through multiple mechanisms