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The presence of cysteine, with the thiol group (-SH), gives glutathione a remarkable ability to oxidize, an ability that is used in living systems to neutralize oxidizing substances such as oxygen radicals, preventing the latter from reacting to damage important biological molecules, such as enzymes or nucleic acids

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Necroptosis is an important severity determinant and potential therapeutic target in experimental severe pancreatitis

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doi:10.1007/s00262-019-02478-7