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A possible explanation for the early worsening in retinopathy in the SUSTAIN-6 trial is the rapid improvement in glycemic control (65)

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Zepbound (tirzepatide), manufactured by Fortune 500 firm Eli Lilly & Co., bested competitor Wegovy (semaglutide), a product of Global 500 company Novo Nordisk, in a recent randomized clinical trial backed by Lilly

Bernardout M, Le Gresley A, ElShaer A, Wren SP

This lengthy process can take over a decade and often results in substantial financial losses if a drug fails to gain approval or does not perform as expected in the market

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