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[5] Notably, normal feedback mechanisms remain intact: elevated IGF-1 and GH can signal the hypothalamus and pituitary to modulate further hormone release, which may reduce the risk of extreme hormone levels

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The peptide is primarily degraded through proteolysis rather than renal excretion, so kidney function is less critical than with some other drugs

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Switching from Ozempic to Wegovy could bring significant weight loss benefits, but there are also factors to consider: Side effects: Both drugs can cause side effects, most commonly gastrointestinal problems