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Risks and Warnings Both drugs carry warnings for: Possible thyroid C-cell tumors Pancreatitis Kidney damage in rare cases (due to dehydration from nausea) Neither is recommended for people with a personal or family history of medullary thyroid carcinoma
Tirzepatide engages two (GLP-1 plus GIP, dual)
alternatives include SGLT2 inhibitors, DPP-4 inhibitors, insulin, or specialist allergy assessment for switching agents
R.WefersJ.MeierJ
Prior therapy and weight loss Adults who used semaglutide as their first obesity medication lost more body weight at all timepoints than those who used a previous obesity medication
So there are other options available, but they may be less effective, he added
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