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In addition to pathogenic role, KCs also contribute to protection against AILI by producing some hepato-regulatory cytokines and mediators, including IL-6, IL-10, IL-18 binding protein and complement 1q (C1q) [42]
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Methimazole is an oral antithyroid drug that has recently attracted attention due to its depigmenting effect by inhibiting peroxidase, but it has also been shown to exert inhibitory effects on tyrosinase in experimental studies
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