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Sesquiterpenoids and lignans from the roots of Syringa pinnatifolia

A substantial body of work establishes that the nuclear hormone receptor, NHR-49, is essential for activating and repressing the expression of genes involved in -oxidation during starvation and plays a critical role in animal physiology and lifespan determination 16

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This leaves you open to oxidative damage caused by reactive oxygen species (aka free radicals)

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