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The transcriptome analysis revealed that overexpression of VaPAT1 ( Phytochrome A signal transduction 1 ) and VaIDD3 (INDETERMINATE-DOMAIN 3) enhanced cold tolerance in plants by modulating expression of lipoxygenase 3 ( LOX3 ), gene involved in JA biosynthesis [126] (Fig

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Long-term consumption of food-derived chlorogenic acid protects mice against acetaminophen-induced hepatotoxicity via promoting PINK1-dependent mitophagy and inhibiting apoptosis

It often manifests as a burning sensation in the chest, just behind the breastbone, and is usually related to acid reflux or gastroesophageal reflux disease (GERD)

This is further supported by the finding that SOD activity is increased during active disease and returns to normal in remission (157).Additionally, the presence of oxidative damage and the inhibition of catalase, an antioxidant enzyme, in CD patients immune cells further underscores oxidative stresss role in the disease (158)