Current evidence suggests GLP-1 medications work best as long-term treatment, similar to blood pressure or cholesterol medications
This happens when free radicals build up and damage your cells
Efficacy and safety of co-administered once-weekly cagrilintide 2.4 mg with once-weekly GLP1 2.4 mg in type 2 diabetes: a multicentre, randomised, double-blind, active-controlled, phase 2 trial
Protection of cholinergic and antioxidant system contributes to the effect of berberine ameliorating memory dysfunction in rat model of streptozotocin-induced diabetes. Behavioural brain research 220.1 (2011): 30-41.
Start Low, Go Slow Dose increased gradually over several weeks to minimize side effects
Cardiovascular benefits associated with some GLP-1 receptor agonists (semaglutide, dulaglutide, liraglutide) observed in clinical trials are likely to diminish after discontinuation, though the exact persistence of these benefits remains uncertain