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In an exploratory analysis of REWIND, the hazard of substantive cognitive impairment was reduced by 14% in the dulaglutide group [62]
Early inhibition of phosphodiesterase 4B (PDE4B) instills cognitive resilience in APPswe/PS1dE9 mice
As in PWA mice, such body weight loss was accompanied by a significant decrease in food intake and fat mass (Fig
The program is also now covering nutrition counseling
Duckworth W, Abraira C, Moritz T, et al
Bispecific molecules are more often designed to target antigens expressed on the same cell or cells within the same environment but our data also demonstrates the feasibility of achieving dual pharmacology when targeting molecules in very different compartments: a soluble serum protein (PCSK9) and a GPCR predominately expressed in pancreatic -cells (GLP-1R)
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