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Laboratory data indicate that GHK-Cu may affect extracellular-matrix-related readouts in cultured cells and animal research models
Here's the honest data point: in a review of higher-dose IV glutathione (1,200 mg twice weekly for six weeks), about a third of participants experienced adverse events, including liver dysfunction and one case of anaphylaxis (Alzahrani et al., 2025)
Do not vigorously aspirate in immunization-style injections, but ensure not in a blood vessel (striking a vein is unlikely in recommended sites)
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The results of the immunofluorescence staining in the gastrocnemius muscle at 8 weeks showed that ROS accumulation and release increased after SCI, the ROS-positive cell rate increased significantly, the percentage of ROS-positive area also increased, and the immunofluorescence intensity was significantly enhanced