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GDF8 and activin A blockade protects against GLP-1induced muscle loss while enhancing fat loss in obese male mice and non-human primates
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Exercise does not significantly alter the pharmacokinetics of semaglutide, meaning it does not change how the drug is absorbed or how quickly it acts
The phase 2 trial used the same starting doses across all participants regardless of body weight, and the GI side effect profile was similar across weight categories
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