Follows the argument that goes: it doesnt matter about statistical significance etc because my body is unique so it might work for me, and I know and I should be able to choose. Often when it goes wrong, people then claim they should have been prevented from doing a reckless thing
If youre on a weight loss journey, definitely give this company a try! I am now in month 3 and have lost 17 lbs in 9 weeks
From a more general point of view, it is particularly interesting that these drugs exert their therapeutic action by acting on the brain to reduce appetite and thus create a significant caloric deficit
Our complete semaglutide vs tirzepatide comparison guide covers this in detail, but here are the key differences in weight loss outcomes: Average Weight Loss Comparison Semaglutide (STEP-1 trial, 68 weeks): Average weight loss: 14.9% 69.1% lost 10% or more 50.5% lost 15% or more Tirzepatide (SURMOUNT-1 trial, 72 weeks at 15 mg dose): Average weight loss: 22.5% 89% lost 10% or more 78% lost 15% or more Tirzepatide shows higher average weight loss in clinical trials, though both medications demonstrate significant effectiveness
In human fibroblast cultures, this has been shown to extend the "Hayflick limit" (the number of times a cell can divide) by over 10 passages
Researchers are not measuring weight, A1C, or relapse rate