There is no established upper limit for B12 intake due to its low risk of toxicity
Fontes Sikiric P, Hahm KB, Blagaic AB, et al
Not everyone taking tirzepatide will need B12 supplementation
Cross-compound receptor-occupancy percentages are deliberately not compared here: occupancy (pRO) is a modeled inference, not a measurement, and Willard 2020 cautions that "calculating pRO values has caveats." These EC50s measure functional potency, not binding affinity
Walk in during our open hours and a member of our nurse-practitioner-led team will administer your B12 shot, usually within ten minutes of arrival
Similarly, anyone experiencing unexplained fatigue, weakness, neurological symptoms (such as numbness, tingling or problems with balance), or difficulty losing weight despite appropriate lifestyle measures should consult their GP