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However, these metabolic benefits are often counterbalanced by complications such as hypoglycemia, stemming from mechanisms like altered nutrient absorption, exaggerated insulin responses, and increased incretin secretion [16, 17]
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In experimental models, researchers often measure oxygen consumption, substrate oxidation patterns, metabolic biomarkers, and energy balance parameters to evaluate how receptor activation influences energy utilization across tissues
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( G ) Prolonged activation of LS GLP-1R neurons suppresses food intake
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