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In research settings, activation of these pathways is analysed in terms of regulation of glucose metabolism, glucose-dependent insulin secretion, modulation of glucagon secretion and mechanisms related to the satiety axis

Continuous GH exposure (as seen with daily subcutaneous recombinant GH injections) downregulates GH receptors in hepatic and muscle tissue over time

(2014) 100(Suppl 1):496S502S

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Yang WS, SriRamaratnam R, Welsch ME, Shimada K, Skouta R, Viswanathan VS, Cheah JH, Clemons PA, Shamji AF, Clish CB, et al

Current concepts in management of weight regain following bariatric surgery