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3.4 Appetite regulation and weight management Similar to animal studies with deletion of the GIPR gene that exhibit protection toward obesity (53), early genome-wide association studies (GWAS) in humans have revealed the GIPR gene to be associated with BMI (103)
Eligibility typically requires a BMI of 35 or above (or 30+ with weight-related conditions), documented attempts at weight loss, and a referral to specialist services
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What is GLP-1, anyway
They typically contain ingredients such as glutathione, vitamin C, alpha-lipoic acid, and plant-based antioxidants
Gastroenterology 141:150156 Gier B, Matveyenko AV, Kirakossian D, Dawson D, Dry SM, Butler PC (2012) Chronic GLP-1 receptor activation by exendin-4 induces expansion of pancreatic duct glands in rats and accelerates formation of dysplastic lesions and chronic pancreatitis in the Kras(G12D) mouse model
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