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It has a molecular weight of 247.72 g/mol and a density of 1.143 g/cm3

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As such, a deficiency in ATP synthase activity leads to increased m and restriction of mitochondrial respiration, thereby limiting the generation of ATP and NAD+ via mitochondrial respiration [66]

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This is consistent with the fact that examination of the fatty-acid oxidation pathway in fibroblast culture did not reveal any abnormalities to explain the elevations in acyl-carnitines

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These events are reversed by modulators that turn off or degrade these signaling molecules and a negative feedback inhibition that modulates the signal itself

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The Journal of Biological Chemistry

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