Most men trying the hack fell into three camps: those wanting to cut calories without willpower battles, gym-goers chasing faster recovery, and guys in their late 30s and 40s interested in supporting natural testosterone
Mechanism involves NO system modulation (homeostatic regulationupregulating when deficient, moderating when excessive), VEGF/VEGFR2 upregulation for angiogenesis, FAK-paxillin pathway activation for cell migration (40% increase per Chang et al.), and EGR-1 transcription factor upregulation for growth factor sensitivity
The main reason it is used in skin care is that it contains natural AHA acids, namely Malic and Tartaric, and hence why it supposedly helps slough off dead skin cells in combination with other acid-containing fruit extracts as part of the trade name ACB Fruit Mix
10.3390/diseases9020039 234
The ascorbate-glutathione pathway (Halliwell-Asada cycle) is an indispensible component of the ROS homeostasis mechanism of plants
These creams lighten the skin by reducing the amount of melanin in the skin