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doi: 10.1530/EJE-14-0990 73 WierinckxADelgrangeEBertolinoPFranoisPChansonPJouanneauEet al

In the absence of phosphorylation during the early G1 phase, pRb engages with E2F transcription factors and suppresses the transcription of the E2F-regulated genes

This compromises its ability to fertilize an egg

2656383-23-0 Chemical Name: Tirzepatide intermediate P10 Synonyms Tirzepatide intermediate P10;(S)-N-((S)-1-Amino-3-(tert-butoxy)-1-oxopropan-2-yl)-1-(O-(tert-butyl)-N-(O-(tert-butyl)-N-glycyl-L-prolyl-L-seryl)-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl)pyrrolidine-2-carboxamide, 2,2,2-trifluoroacetate salt CBNumber: CB212810550 Molecular Formula: C48H81N11O13.C2HF3O2 Molecular Weight: 1134.25 MDL Number: MOL File: 2656383-23-0.mol MSDS File: SDS Last updated:2026-05-27 23:55:13 Tirzepatide intermediate P10 Preparation Products And Raw materials Raw materials Preparation Products Tirzepatide intermediate P10 (S)-N-((S)-1-Amino-3-(tert-butoxy)-1-oxopropan-2-yl)-1-(O-(tert-butyl)-N-(O-(tert-butyl)-N-glycyl-L-prolyl-L-seryl)-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl)pyrrolidine-2-carboxamide, 2,2,2-trifluoroacetate salt 2656383-23-0 C50H82F3N11O15

Gastroenterology 158 , 17131727 (2020)

Abbreviations GLP-1RAs: Glucagon-like peptide 1 receptor agonists GLP-1: Glucagon-like peptide 1 ADRs: Adverse drug reactions SSIBs: Suicidal or self-injurious behaviors EMA: European Medicines Agency FDA: The Food and Drug Administration FAERS: The Food and Drug Administration Adverse Event Reporting System MedDRA: The Medical Dictionary for Regulatory Activities TTO: Time-to-onset CI: Confidence interval IC: Information Component References Lingvay I, Leiter LA