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A signaling view into the inflammatory tumor microenvironment

Glucagon-like peptide 1 potentiates glucotoxicity-diminished insulin secretion via stimulation of cAMP-PKA signaling in INS-1E cells and mouse islets

doi: 10.1053/j.gastro.2023.02.022 77 LiangYShiXShenYHuangZWangJShaoCet al

Sackmann-Sala, L., et al

This may explain the differences observed between pre-clinical and clinical studies or even discrepancies between different clinical studies